Compound ID | 2684

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Porothramycin

Class: Natural product antibiotic

Spectrum of activity: Gram-positive
Details of activity: Active against Staphylococcus aureus, Enterococcus faecalis, Clostridium difficile, and Clostridium perfringes; DNA alkylating compound
Description: Natural product from Streptomyces albus; an anthramycin-type antibiotic
Institute where first reported: Bristol-Myers Research Institute, Tokyo Research Center, 2-9-3 Shimo-meguro, Meguro-ku, Tokyo 153, Japan
Year first mentioned: 1988
Development status: Experimental
Chemical structure(s):
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Molecular weight: 343.38
Iso. SMILES: CN(C)C(=O)/C=C/C1=CN2C(C1)[C@H](NC3=C(C2=O)C=CC=C3OC)O
InChI Key: OQMYRVPMCIOFHL-GCOHUWJYSA-N
Can. SMILES: CN(C)C(=O)/C=C/C1=CN2C(C1)[C@H](NC3=C(C=CC=C3C2=O)OC)O
InChI: InChI=1S/C18H21N3O4/c1-20(2)15(22)8-7-11-9-13-17(23)19-16-12(18(24)21(13)10-11)5-4-6-14(16)25-3/h4-8,10,13,17,19,23H,9H2,1-3H3/b8-7+/t13?,17-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/6439234
Citations:
  • https://link.springer.com/article/10.1007/s12223-014-0339-x
  • https://www.jstage.jst.go.jp/article/antibiotics1968/41/10/41_10_1366/_pdf/-char/en

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