Compound ID | 2685

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Portmicin

Class: Natural product antibiotic

Spectrum of activity: Gram-positive
Details of activity: Active against Staphylococcus aureus, Mycobacterium smegmatis, and Mycobacterium avium (also shows coccidiostat activity)
Description: Natural product from Nocardiopsis sp.; a polyether
Institute where first reported: Tokyo Research Laboratories, Kaken Pharmaceutical Co., Ltd., 2-28-8, Honkomagome, Bunkyo-ku,
Year first mentioned: 1987
Development status: Experimental
Chemical structure(s):
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Molecular weight: 829.07
Iso. SMILES: CC[C@H]([C@@]1(C[C@@H]([C@](O1)([C@H]2C[C@@H]([C@@H](O2)[C@@]3(C[C@H]([C@@H](O3)[C@@H]4CC[C@@]5(O4)[C@@H]([C@@H]([C@H]([C@H](O5)[C@@H](C)[C@H]([C@H](C)C(=O)O)OC)C)OC)C)O[C@H]6CC[C@@H]([C@H](O6)C)OC)C)C)O)C)C)O
InChI Key: NEIZBXNLNGSVCX-MJDUMZDQSA-N
Can. SMILES: CC[C@H]([C@]1(C)C[C@H](C)[C@]([C@H]2C[C@H](C)[C@H]([C@]3(C)C[C@H]([C@H]([C@@H]4CC[C@]5([C@H](C)[C@@H]([C@@H](C)[C@@H]([C@@H](C)[C@H]([C@H](C)C(=O)O)OC)O5)OC)O4)O3)O[C@H]6CC[C@@H]([C@@H](C)O6)OC)O2)(O)O1)O
InChI: InChI=1S/C44H76O14/c1-14-32(45)41(9)20-23(3)44(48,58-41)33-19-22(2)39(54-33)42(10)21-31(53-34-16-15-29(49-11)28(8)52-34)38(56-42)30-17-18-43(55-30)27(7)37(51-13)25(5)36(57-43)24(4)35(50-12)26(6)40(46)47/h22-39,45,48H,14-21H2,1-13H3,(H,46,47)/t22-,23-,24-,25-,26-,27+,28+,29-,30-,31+,32+,33+,34-,35+,36+,37+,38-,39+,41-,42-,43-,44-/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/11765995
Citation: https://www.jstage.jst.go.jp/article/antibiotics1968/40/2/40_2_237/_pdf/-char/en

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