Compound ID | 2715

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Cyanomycin

Synonym(s): Pyocyanin

Class: Natural product antibiotic

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus and Escherichia coli; induces production of reactive oxygen species
Description: Natural product from Streptomyces cyanoflavus (or pyocyanin from Pseudomonas aeruginosa); antibiotic pigment
Institute where first reported: Research Laboratory, Meiji Milk Products, Co; The Squibb Institute for Medical Research NJ USA
Year first mentioned: 1958
Development status: Experimental
Chemical structure(s):
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Molecular weight: 210.23
Iso. SMILES: CN1C2=CC=CC=C2N=C3C1=CC=CC3=O
InChI Key: YNCMLFHHXWETLD-UHFFFAOYSA-N
Can. SMILES: CN1C2=C(C=CC=C2)N=C3C1=CC=CC3=O
InChI: InChI=1S/C13H10N2O/c1-15-10-6-3-2-5-9(10)14-13-11(15)7-4-8-12(13)16/h2-8H,1H3
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/6817
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/22/2/22_2_49/_pdf
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC293551/pdf/jbacter00562-0172.pdf
  • https://www.jstage.jst.go.jp/article/antibioticsa/11/4/11_143/_pdf

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