Compound ID | 2724

Update compound information

Saframycin Mx1

Class: Natural product antibiotic

Agent Type: Natural product; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Nucleic acid (DNA and RNA) synthesis inhibitor
Target Pathogen: Active against Staphylococcus aureus, Brevibacterium ammoniagenes, Escherichia coli, and Pseudomonas aeruginosa
Description: Natural product from Myxococcus xanthus strain Mx x 48; resembles saframycin produced by Streptomyces but has a side chain ending in alanine instead of pyruvic acid
Year first mentioned: 1987
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 586.63
Iso. SMILES: CC1=C(C2=C([C@H]3[C@@H]4CC5=C([C@@H](N4[C@H]([C@@H]([C@H]2OC)N3C)O)CNC(=O)[C@H](C)N)C(=O)C(=C(C5=O)C)OC)C(=C1OC)O)O
InChI Key: QSLZNGPMBOCIAZ-QSNGQZDXSA-N
Can. SMILES: CC1=C(C(=O)C2=C(C[C@H]3[C@@H]4C5=C(C(=C(C)C(=C5[C@@H]([C@H]([C@@H](N3[C@H]2CNC(=O)[C@H](C)N)O)N4C)OC)O)OC)O)C1=O)OC
InChI: InChI=1S/C29H38N4O9/c1-10-21(34)13-8-14-19-17-18(22(35)11(2)26(41-6)24(17)37)27(42-7)20(32(19)4)29(39)33(14)15(9-31-28(38)12(3)30)16(13)23(36)25(10)40-5/h12,14-15,19-20,27,29,35,37,39H,8-9,30H2,1-7H3,(H,31,38)/t12-,14-,15-,19+,20+,27-,29-/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/3036879
Citation: https://www.jstage.jst.go.jp/article/antibiotics1968/41/8/41_8_993/_article

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.