Compound ID | 2737

Update compound information

Sorbistin

Class: Aminoglycoside

Agent Type: Natural product; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Unknown
Target Pathogen: Active against Staphylococcus aureus, Diplococcus pneumoniae, Klebsiella pneumoniae, Proteus mirabilis, Proteus vulgaris, Pseudomonas aeruginosa, and Escherichia coli (including strains expressing AAC(6')-I, AAC(3)-I, ANT(2))"
Description: Natural product from Pseudomonas sp.
Institute where first reported: Bristol-Banyu Research Institute, Ltd.
Year first mentioned: 1976
Development status: Experimental
Chemical structure(s):
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Molecular weight: 383.4
Iso. SMILES: CC(=O)N[C@@H]1[C@H](O[C@@H]([C@@H]([C@H]1O)O)O[C@H]([C@H](CN)O)[C@@H]([C@@H](CO)O)N)CO
InChI Key: UWAJGPKPIKRBHZ-BOPCDOEQSA-N
Can. SMILES: CC(=O)N[C@@H]1[C@@H](CO)O[C@@H]([C@@H]([C@H]1O)O)O[C@H]([C@H](CN)O)[C@@H]([C@@H](CO)O)N
InChI: InChI=1S/C14H29N3O9/c1-5(20)17-10-8(4-19)25-14(12(24)11(10)23)26-13(6(21)2-15)9(16)7(22)3-18/h6-14,18-19,21-24H,2-4,15-16H2,1H3,(H,17,20)/t6-,7+,8+,9+,10+,11-,12+,13+,14+/m0/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/173742
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/23/1/23_1_13/_article
  • https://www.jstage.jst.go.jp/article/antibiotics1968/29/11/29_11_1137/_pdf/-char/en

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