Compound ID | 2745

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Streptogramin

Class: Streptogramin

Spectrum of activity: Gram-positive
Details of activity: Active against Staphylococcus aureus; streptogramin A mainly active against Gram-positive cocci; streptogramin B mainly active against Gram-positive bacilli; streptogramin A is a protein synthesis inhibitor
Description: Natural product from Streptomyces graminofmiens; composed of streptogramin A (syn. Virginiamycin M1) and streptogramin B (syn. pristinamycin IA)
Year first mentioned: 1953
Development status: Experimental
Chemical structure(s):
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Molecular weight: 525.59
Iso. SMILES: C[C@@H]1/C=C/C(=O)NC/C=C/C(=C/[C@H](CC(=O)CC2=NC(=CO2)C(=O)N3CCC=C3C(=O)O[C@@H]1C(C)C)O)/C
InChI Key: DAIKHDNSXMZDCU-FQTGFAPKSA-N
Can. SMILES: CC(C)[C@@H]1[C@H](C)/C=C/C(=O)NC/C=C/C(=C/[C@H](CC(=O)CC2=NC(=CO2)C(=O)N3CCC=C3C(=O)O1)O)/C
InChI: InChI=1S/C28H35N3O7/c1-17(2)26-19(4)9-10-24(34)29-11-5-7-18(3)13-20(32)14-21(33)15-25-30-22(16-37-25)27(35)31-12-6-8-23(31)28(36)38-26/h5,7-10,13,16-17,19-20,26,32H,6,11-12,14-15H2,1-4H3,(H,29,34)/b7-5+,10-9+,18-13+/t19-,20-,26-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/5459319
Citation: https://www.microbiologyresearch.org/content/journal/micro/10.1099/00221287-42-1-93

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