Compound ID | 2762

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Tetranactin

Class: Natural product antibiotic

Spectrum of activity: Gram-positive
Details of activity: Active against Staphylococcus aureus and Mycobacterium tuberculosis
Description: Natural product from Streptomyces sp.; shows insecticidal properties; a macrotetrolide
Institute where first reported: Research Laboratories, Chugai Pharmaceutical Co., Ltd., Tokyo, Japan
Year first mentioned: 1971
Development status: Experimental
Chemical structure(s):
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Molecular weight: 793.04
Iso. SMILES: CC[C@H]1C[C@@H]2CC[C@@H](O2)[C@H](C(=O)O[C@@H](C[C@H]3CC[C@H](O3)[C@@H](C(=O)O[C@H](C[C@@H]4CC[C@@H](O4)[C@H](C(=O)O[C@@H](C[C@H]5CC[C@H](O5)[C@@H](C(=O)O1)C)CC)C)CC)C)CC)C
InChI Key: NKNPHSJWQZXWIX-DCVDGXQQSA-N
Can. SMILES: CC[C@H]1C[C@@H]2CC[C@H]([C@@H](C)C(=O)O[C@H](CC)C[C@H]3CC[C@@H]([C@H](C)C(=O)O[C@@H](CC)C[C@@H]4CC[C@H]([C@@H](C)C(=O)O[C@H](CC)C[C@H]5CC[C@@H]([C@H](C)C(=O)O1)O5)O4)O3)O2
InChI: InChI=1S/C44H72O12/c1-9-29-21-33-13-17-38(49-33)26(6)42(46)54-31(11-3)23-35-15-19-40(51-35)28(8)44(48)56-32(12-4)24-36-16-20-39(52-36)27(7)43(47)55-30(10-2)22-34-14-18-37(50-34)25(5)41(45)53-29/h25-40H,9-24H2,1-8H3/t25-,26+,27+,28-,29-,30+,31+,32-,33-,34+,35+,36-,37-,38+,39+,40-
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/441165
Citations:
  • https://www.sciencedirect.com/science/article/pii/0162310988900471?via%3Dihub
  • https://www.jstage.jst.go.jp/article/antibiotics1968/24/6/24_6_347/_pdf/-char/en

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