Compound ID | 2797
NCR992
Class: Antimicrobial peptide
| Agent Type: | Natural product; Direct acting; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Membrane-active agent |
| Target Pathogen: | Active against Klebsiella pneumoniae |
| Description: | Natural product from the legume plant Medicago truncatula; nodule-specific cysteine-rich (NCR) peptide with variants that show improved activity and less toxicity towards mammalian cells; effective ex vivo |
| Institute where first reported: | Medical Laboratories Technology Department, College of Applied Medical Sciences, Taibah University, Medina, Saudi Arabia |
| Year first mentioned: | 2024 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://journals.asm.org/doi/10.1128/spectrum.01827-23 |
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