Compound ID | 2800
φPaP11-13
Synonym(s): phi-PaP11-13
Class: Bacteriophage and/or bacteriophage-derived product
| Agent Type: | Natural product; Indirect acting; Bacteriophage or bacteriphage-derived product; Antivirulence; |
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | Attenuates infection caused by C. acnes in rat infection model |
| Target Pathogen: | Active against Cutibacterium/Propionibacterium acnes |
| Description: | Bacteriophage from sewage collected in a medical wastewater treatment center; reduces inflammation and supresses induced inhibition of keratinocyte apoptosis by C. acnes |
| Institute where first reported: | Department of Plastic and Cosmetic Surgery, Xinqiao Hospital, Army Medical University (the Third Military Medical University), Chongqing, China |
| Year first mentioned: | 2024 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://journals.asm.org/doi/10.1128/spectrum.02838-23 |
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