Compound ID | 2819

Update compound information

NSC367428

Synonym(s): NSC 367428  |  NSC-367428

Class: Folate synthesis inhibitor

Spectrum of activity: Gram-negative
Details of activity: Active against Escherichia coli
Description: Synthetic compound identified from screening the National Cancer Institute (NCI) diversity set V library of compounds ***check Source reference for other active compounds reported
Institute where first reported: Division of Pharmacology and Pharmaceutical Sciences, School of Pharmacy, University of Missouri-Kansas City, Kansas City, Missouri, USA
Year first mentioned: 2023
Development status: Experimental
Chemical structure(s):
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Molecular weight: 220.16
Iso. SMILES: COC1C(C(=O)NC(=O)N1)(C(=O)OC)F
InChI Key: CMZYDQKKDNXWKW-UHFFFAOYSA-N
Can. SMILES: COC1C(C(=O)NC(=O)N1)(C(=O)OC)F
InChI: InChI=1S/C7H9FN2O5/c1-14-4-7(8,5(12)15-2)3(11)9-6(13)10-4/h4H,1-2H3,(H2,9,10,11,13)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/339703
Citation: https://journals.asm.org/doi/10.1128/spectrum.00541-23#T3

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