Compound ID | 2820
B59
Class: Small molecule antibacterial agent
| Agent Type: | Synthetic; Small molecule; Direct acting; |
| Spectrum of activity: | Antimycobacterial |
| Mechanism of action: | Dihydrodipicolinate reductase inhibitor |
| Target Pathogen: | Active against Mycobacterium tuberculosis |
| Description: | Synthetic small molecule compound from NCI Open Database library identified by in silico-based virtual screening; shows no cytotoxicity towards mammalian cell line (highest concentration tested 200 ug/ml) |
| Institute where first reported: | Department of Biochemistry, University of Delhi South Campus, New Delhi, India |
| Year first mentioned: | 2023 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://journals.asm.org/doi/10.1128/spectrum.01359-23 |
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