Compound ID | 2827
Class: Antimicrobial peptide
Spectrum of activity: | Gram-negative |
Details of activity: | Active against multidrug-resistant and susceptible Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli (shows more potent activity vs Cecropin HC10); disrupts integrity of cell membrane (membrane-active agent) |
Description: | Natural product from fly Hermetia illucens; 44 amino acid long; low haemolytic property |
Institute where first reported: | Laboratory of Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium |
Year first mentioned: | 2022 |
Development status: | Experimental |
External links: | |
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