Compound ID | 2827

Cecropin HC1 (Hill-Cec1)

Class: Antimicrobial peptide

Spectrum of activity: Gram-negative
Details of activity: Active against multidrug-resistant and susceptible Pseudomonas aeruginosa, Klebsiella pneumoniae, and Escherichia coli (shows more potent activity vs Cecropin HC10); disrupts integrity of cell membrane (membrane-active agent)
Description: Natural product from fly Hermetia illucens; 44 amino acid long; low haemolytic property
Institute where first reported: Laboratory of Microbiology, Parasitology and Hygiene (LMPH), Faculty of Pharmaceutical, Biomedical and Veterinary Sciences, University of Antwerp, Antwerp, Belgium
Year first mentioned: 2022
Development status: Experimental

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