Compound ID | 2840

Cesin A

Synonym(s): Cesin

Class: Antimicrobial peptide

Spectrum of activity: Gram-positive
Details of activity: Active against Lactococcus lactis, Listeria monocytogenes, methicillin-resistant and -susceptible Staphylococcus aureus, Enterococcus faecium, Enterococcus faecalis, and Clostridium perfringens; cell wall synthesis (binds to lipid II) and lipoteichoic acid inhibitor
Description: Natural product from Clostridium estertheticum initially identified by targeted genome mining; short natural variant of nisin; a lantibiotic
Institute where first reported: Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, the Netherlands
Year first mentioned: 2022
Development status: Experimental

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