Compound ID | 2840
Cesin A
Synonym(s): Cesin
Class: Antimicrobial peptide
| Agent Type: | Natural product; Direct acting; |
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | Cell wall synthesis inhibitor. Cell wall synthesis (binds to lipid II) and lipoteichoic acid synthesis inhibitor |
| Target Pathogen: | Active against Lactococcus lactis, Listeria monocytogenes, methicillin-resistant and -susceptible Staphylococcus aureus, Enterococcus faecium, Enterococcus faecalis, and Clostridium perfringens |
| Description: | Natural product from Clostridium estertheticum initially identified by targeted genome mining; short natural variant of nisin; a lantibiotic |
| Institute where first reported: | Department of Molecular Genetics, Groningen Biomolecular Sciences and Biotechnology Institute, University of Groningen, Groningen, the Netherlands |
| Year first mentioned: | 2022 |
| Development status: | Experimental |
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