Compound ID | 2843

Update compound information

Eugenol

Synonym(s): 4-Allyl-2-methoxyphenol

Class: Small molecule antibacterial agent

Spectrum of activity: Gram-negative
Details of activity: Active against colistin-resistant Pseudomonas aeruginosa and Klebsiella pneumoniae
Description: Natural product; shows antibacterial effect against Escherichia coli harbouring mcr-1 gene when in combination with colistin; shows no antibacterial activity alone; an antibiotic adjuvant
Institute where first reported: Wenzhou Medical University, Wenzhou, Zhejiang Province, China
Year first mentioned: 2023
Development status: Experimental
Chemical structure(s):
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Molecular weight: 164.2
Iso. SMILES: COC1=C(C=CC(=C1)CC=C)O
InChI Key: RRAFCDWBNXTKKO-UHFFFAOYSA-N
Can. SMILES: C=CCC1=CC=C(C(=C1)OC)O
InChI: InChI=1S/C10H12O2/c1-3-4-8-5-6-9(11)10(7-8)12-2/h3,5-7,11H,1,4H2,2H3
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/3314
Citation: https://journals.asm.org/doi/10.1128/spectrum.03666-22

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