Compound ID | 2854
Class: Bacteriophage and/or bacteriophage-derived product
| Agent Type: | Natural product; Direct acting; Bacteriophage or bacteriphage-derived product; |
| Spectrum of activity: | Gram-negative |
| Mechanism of action: | Membrane-active agent. Disrupts integrity of outer cell membrane (membrane-active agent) facilitating its movement to hydrolyse peptidoglycan |
| Target Pathogen: | Active against Escherichia coli, Salmonella enterica serovar Enteritidis, Pseudomonas aeruginosa, and Staphylococcus aureus |
| Description: | Synthetic endolysin; random peptide fused with endolysin Bp7e (chimeric endolysin) |
| Institute where first reported: | College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China |
| Year first mentioned: | 2023 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://journals.asm.org/doi/10.1128/aem.00581-23 |