Compound ID | 2854

Artificial-Bp7e6 endolysin (Art-Bp7e6)

Class: Bacteriophage and/or bacteriophage-derived product

Spectrum of activity: Gram-negative
Details of activity: Active against Escherichia coli, Salmonella enterica serovar Enteritidis, Pseudomonas aeruginosa, and Staphylococcus aureus; disrupts integrity of outer cell membrane (membrane-active agent) facilitating its movement to hydrolyse peptidoglycan
Description: Synthetic endolysin; random peptide fused with endolysin Bp7e (chimeric endolysin)
Institute where first reported: College of Veterinary Medicine, Qingdao Agricultural University, Qingdao, China
Year first mentioned: 2023
Development status: Experimental

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