Compound ID | 2863

Update compound information

Antibiotic 2B5

Synonym(s): 2-aminoimidazole derivative

Class: Antibiofilm agent

Spectrum of activity: Gram-positive
Details of activity: Active against Staphylococcus aureus and Streptococcus mutans; targets VicR or VicR homolog (for Staphylococcus aureus) which regulates biofilm matrix producing enzymes Gtfs
Description: Synthetic compound containing 2-aminoimidazole derived from marine alkaloid
Institute where first reported: University of Alabama at Birmingham Schools of Dentistry and Medicine, Birmingham, Alabama, USA
Year first mentioned: 2023
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 415.06
Iso. SMILES: NC1=NC(CCCC(NCCCCCCCCCCCCCCC)=O)=CN1.Cl
InChI Key: JLMQZZOBJOEUAJ-UHFFFAOYSA-N
Can. SMILES: CCCCCCCCCCCCCCCNC(=O)CCCC1=CNC(=N1)N.Cl
InChI: InChI=1S/C22H42N4O.ClH/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18-24-21(27)17-15-16-20-19-25-22(23)26-20;/h19H,2-18H2,1H3,(H,24,27)(H3,23,25,26);1H
External links:
Citation: https://journals.asm.org/doi/10.1128/mbio.00137-23

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.