Compound ID | 2865
Thymol-decorated gold nanoparticle (Thymol_Au NPs)
Class: Membrane-active agent
| Spectrum of activity: | Gram-negative |
| Details of activity: | Active against the following: tigecycline-resistant Acinetobacter baumannii and Klebsiella pneumoniae; colistin-resistant Acinetobacter baumannii, Escherichia coli, Enterobacter cloacae, Klebsiella pneumoniae , and Pseudomonas aeruginosa; ceftazidime-avibactam-resistant Escherichia coli, Enterobacter cloacae, Klebsiella pneumoniae, and Pseudomonas aeruginosa |
| Description: | Synthetic compound; gold nanoparticle carrying natural phenol; the thymol and gold nanoparticle do not possess any antibacterial activity on their own |
| Institute where first reported: | Key Laboratory of Clinical Laboratory Diagnosis and Translational Research of Zhejiang Province, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China |
| Year first mentioned: | 2023 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://journals.asm.org/doi/10.1128/msphere.00549-22 |
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