Compound ID | 287

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BMS 181139

Class: Beta-lactam (carbapenem)

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Broad spectrum antibiotic which demonstrated potent activity against E. coli, K. pnemoniae, P. aeruginosa and S. aureusto name a few. BMS-181139 does not show cross resistance to imipenem resistant P. aeruginosa
Description: Kessler RE, Fung-Tomc J, Minassian B, et al. BMS-181139: In vitroactivities in comparison to imipenem and meropenem. 34th-Intersci-Conf-Antimicrobial-Agents-Chemother 1994; 125.
Institute where first reported: Bristol-Myers Squibb, UK
Year first mentioned: 1994
Highest developmental phase: Preclinical
Development status: Inactive
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/substance/274328211
Citations:
  • https://journals.asm.org/doi/epdf/10.1128/aac.39.2.380
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC162547/pdf/390380.pdf
  • https://journals.asm.org/doi/epdf/10.1128/aac.39.2.380

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