Compound ID | 288

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BO-3482

Class: Beta-lactam (carbapenem)

Spectrum of activity: Gram-positive
Details of activity: In mice septicaemia model, BO-3482 demonstrated similar efficacy as vancomycin and was much better than imipenem
Description: Nagano R, Adachi Y, Nakamura K, et al. In vitro and in vivo evaluation of Bo-3482, a novel dithiocarbamate carbacephem. 36th-Intersci-Conf-Antimicrobial-Agents-Chemother 1996; 120.
Institute where first reported: Banyu Pharmaceutical Co., Japan
Year first mentioned: 1996
Highest developmental phase: Preclinical
Development status: Inactive
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/substance/274428154
Citations:
  • https://journals.asm.org/doi/epdf/10.1128/aac.41.10.2282
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC164108/pdf/412282.pdf
  • https://journals.asm.org/doi/epdf/10.1128/aac.41.10.2282

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