Compound ID | 288
BO-3482
Class: Beta-lactam
| Agent Type: | Semisynthetic; Direct acting; |
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | Cell wall synthesis inhibitor |
| Description: | A dithiocarbamate carbapenem; in mice septicaemia model, BO-3482 demonstrated similar efficacy as vancomycin and was much better than imipenem; Nagano R, Adachi Y, Nakamura K, et al. In vitro and in vivo evaluation of Bo-3482, a novel dithiocarbamate carbacephem. 36th-Intersci-Conf-Antimicrobial-Agents-Chemother 1996; 120. |
| Institute where first reported: | Banyu Pharmaceutical Co., Japan |
| Year first mentioned: | 1996 |
| Development status: | Experimental |
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