Compound ID | 2889
F598
Class: Antibody
| Agent Type: | Natural product; Indirect acting; Antibiofilm; Antibody; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Targets poly-N-acetyl-d-glucosamine (PNAG) in microbial surfaces and biofilms |
| Target Pathogen: | Broad-spectrum activity |
| Description: | Human monoclonal antibody; does not react to human tissues and organs (no cross-reactivity to human polysaccharides) |
| Institute where first reported: | Alopexx Pharmaceuticals, LLC |
| Year first mentioned: | 2013 |
| Highest developmental phase: | Phase 2 (NCT03222401) |
| Development status: | Active as of 2024 |
| External links: | |
| Guide to Pharmacology: | F598 |
| Citations: |
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