BB2-50F

Class: Antivirulence agent (bacterial flagellar motor inhibitor)

Details of activity:	Inhibits flagellar motility
Description:	Synthetic compound derived from amiloride (a diuretic drug that inhibits bacterial motility)
Institute where first reported:	School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, New South Wales, Australia
Year first mentioned:	2021
Development status:	Experimental

Chemical structure(s):
Canonical SMILES:	C1CCCN(CC1)C2=NC(=C(C(=O)N=C(N)N)N=C2C3=CC4=C(C=CC=C4)O3)N
Isomeric SMILES:	C1CCCN(CC1)C2=C(N=C(C(=N2)N)C(=O)N=C(N)N)C3=CC4=CC=CC=C4O3
InChI:	InChI=1S/C20H23N7O2/c21-17-16(19(28)26-20(22)23)24-15(14-11-12-7-3-4-8-13(12)29-14)18(25-17)27-9-5-1-2-6-10-27/h3-4,7-8,11H,1-2,5-6,9-10H2,(H2,21,25)(H4,22,23,26,28)
InChI Key:	FSPGYSVEHLETQR-UHFFFAOYSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/135393470

External links:
Main Source:	https://journals.asm.org/doi/pdf/10.1128/jb.00367-21