Compound ID | 2903

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Reutericyclin A

Class: Membrane-active agent

Spectrum of activity: Gram-positive
Details of activity: Active against methicillin-resistant and -susceptible Staphylococcus aureus, Enterococcus faecalis, Lactobacillus sp., and Listeria innocua; dissipates membrane potential
Description: Natural product from Lactobacillus reuteri LTH2584; tetramic acid
Year first mentioned: 2000
Development status: Experimental
Chemical structure(s):
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Molecular weight: 349.47
Iso. SMILES: CCCCCCC/C=C/C(=O)N1[C@@H](C(=C(C1=O)C(=O)C)O)CC(C)C
InChI Key: GNGSBVNLHSNSDF-LPQFERQCSA-N
Can. SMILES: CCCCCCC/C=C/C(=O)N1[C@H](CC(C)C)C(=C(C(=O)C)C1=O)O
InChI: InChI=1S/C20H31NO4/c1-5-6-7-8-9-10-11-12-17(23)21-16(13-14(2)3)19(24)18(15(4)22)20(21)25/h11-12,14,16,24H,5-10,13H2,1-4H3/b12-11+/t16-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/54684555
Citations:
  • https://journals.asm.org/doi/10.1128/aem.69.2.1305-1307.2003
  • https://journals.asm.org/doi/10.1128/aem.66.10.4325-4333.2000

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