Compound ID | 298

Update compound information

KR-21012

Class: Beta-lactam (carbapenem)

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Demonstrated safety in mice in terms of renal, CNS function and behaviour. This is a braod spectrum antibiotic
Description: Kim EJ, Kim JH, Jeong HJ, et al. KR-21012, a new carbapenem: III. Pharmacokinetics and safety studies. 38th-Intersci-Conf-Antimicrobial-Agents-Chemother 1998; 244.
Institute where first reported: Korea Research Institute of Chemical Technology, Korea
Year first mentioned: 1998
Highest developmental phase: Preclinical
Development status: Inactive
Chemical structure(s):
Click here for structure editor
Molecular weight: 305.3
Iso. SMILES: C[C@@H]1[C@@H]2[C@H](C(=O)N2C(=C1[C@H](C(C)C)O)C(=O)[O-])[C@@H](C)O.[Na+]
InChI Key: KVGYHGCCVFNDOI-BGIHSTIZSA-M
Can. SMILES: CC(C)[C@@H](C1=C(C(=O)[O-])N2[C@H]([C@H]1C)[C@@H]([C@@H](C)O)C2=O)O.[Na+]
InChI: InChI=1S/C14H21NO5.Na/c1-5(2)12(17)8-6(3)10-9(7(4)16)13(18)15(10)11(8)14(19)20;/h5-7,9-10,12,16-17H,1-4H3,(H,19,20);/q;+1/p-1/t6-,7+,9+,10+,12-;/m0./s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/129858614
Citation: https://www.sciencedirect.com/science/article/pii/S0960894X99006927?via%3Dihub

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.