Compound ID | 2985
Pep19-2.5
Synonym(s): Peptide Pep 19-2.5
Class: Antimicrobial peptide
| Agent Type: | Synthetic; Indirect acting; Antivirulence; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Binds to bacterial lipopolysaccharide reducing its inflammatory potential of bacterial pathogenicity factors |
| Target Pathogen: | Broad-spectrum activity |
| Description: | Synthetic compound; protects mice against lethal endotoxemia by Salmonella enterica; protected mice from lethal sepsis in combination with other antibiotics |
| Institute where first reported: | Divisions of Biophysics, Research Center Borstel, Borstel, Germany |
| Year first mentioned: | 2013 |
| Highest development stage: | Preclinical |
| Development status: | Experimental |
| External links: | |
| PubChem link: | https://pubchem.ncbi.nlm.nih.gov/substance/472439079 |
| Citation: | https://journals.asm.org/doi/10.1128/aac.02066-12 |
| Patent: | WO2009124721A1 |
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