Compound ID | 2986
SM-295291
Synonym(s): (5R,6S)-6-[(R)-1-hydroxyethyl]-3-{4-[(methoxycarbonylamino)methyl]phenyl}-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Class: Beta-lactam
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Active against methicillin-resistant and -susceptible Staphylococcus aureus, methicillin-resistant and -susceptible Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus agalactiae, Enterococcus faecalis, Enterococcus faecium, Moraxella catarrhalis, Haemophilus influenzae, Klebsiella pneumoniae, Escherichia coli, Enterobacter cloacae, Enterobacter aerogenes, Neisseria gonorrhoeae, Peptostreptococcus sp., and Bacteroides fragilis |
| Description: | Synthetic compound; desmethyl-carbapenems with a structurally unique C-2 side chain (2-aryl carbapenem) |
| Institute where first reported: | Drug Research Division, Dainippon Sumitomo Pharma Co., Ltd., Osaka, Japa |
| Year first mentioned: | 2013 |
| Highest developmental phase: | Preclinical |
| Development status: | Experimental |
| External links: | |
| Citation: | https://journals.asm.org/doi/10.1128/aac.01051-12 |
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