Compound ID | 2986
SM-295291
Synonym(s): (5R,6S)-6-[(R)-1-hydroxyethyl]-3-{4-[(methoxycarbonylamino)methyl]phenyl}-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid
Class: Beta-lactam
| Agent Type: | Synthetic; Small molecule; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Cell wall synthesis inhibitor |
| Target Pathogen: | Active against methicillin-resistant and -susceptible Staphylococcus aureus, methicillin-resistant and -susceptible Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus pyogenes, Streptococcus agalactiae, Enterococcus faecalis, Enterococcus faecium, Moraxella catarrhalis, Haemophilus influenzae, Klebsiella pneumoniae, Escherichia coli, Enterobacter cloacae, Enterobacter aerogenes, Neisseria gonorrhoeae, Peptostreptococcus sp., and Bacteroides fragilis |
| Description: | Synthetic compound; desmethyl-carbapenems with a structurally unique C-2 side chain (2-aryl carbapenem) |
| Institute where first reported: | Drug Research Division, Dainippon Sumitomo Pharma Co., Ltd., Osaka, Japa |
| Year first mentioned: | 2013 |
| Highest development stage: | Preclinical |
| Development status: | Experimental |
| External links: | |
| Citation: | https://journals.asm.org/doi/10.1128/aac.01051-12 |
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