Compound ID | 2999

Update compound information

Croconazole

Synonym(s): 1-[1-[2-[(3-chlorophenyl)methoxy]phenyl]ethenyl]-1H-imidazole

Class: Small molecule antibacterial agent

Details of activity: Active against Mycobacterium ulcerans
Description: Synthetic product (imidazole scaffold); repurposed topical antifungal agent (developed by Shionogi Research Laboratories (Osaka, Japan) and Merz and Co., Frankfurt/Main, Germany under Pilzcin brand name)
Institute where first reported: Swiss Tropical and Public Health Institute, Basel, Switzerland; University of Basel, Basel, Switzerland
Year first mentioned: 2012
Development status: Experimental
Chemical structure(s):
Click here for structure editor
Molecular weight: 310.78
Iso. SMILES: C=C(C1=CC=CC=C1OCC2=CC(=CC=C2)Cl)N3C=CN=C3
InChI Key: WHPAGCJNPTUGGD-UHFFFAOYSA-N
Can. SMILES: C=C(C1=C(C=CC=C1)OCC2=CC=CC(=C2)Cl)N3C=CN=C3
InChI: InChI=1S/C18H15ClN2O/c1-14(21-10-9-20-13-21)17-7-2-3-8-18(17)22-12-15-5-4-6-16(19)11-15/h2-11,13H,1,12H2
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/2880
Citation: https://journals.asm.org/doi/10.1128/aac.01383-12

AntibioticDB is supported by GARDP.

If you have feedback, experience problems, or are interested in a collaboration, please contact us. | Terms and conditions

The content of this site is intended for educational and scientific research purposes only and not as a source of medical advice or consultation.