Compound ID | 3013

Update compound information

Streptothricin BI and Streptothricin BII

Synonym(s): racemomycin E

Class: Streptothricin

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Escherichia coli (BI) and Bacillus subtilis (BII)
Description: Natural product from Streptomyces fradiae; shows delayed toxicity (nephrotoxicity) in mice
Year first mentioned: 1948
Development status: Inactive
Chemical structure(s):
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Molecular weight: 1015.21
Iso. SMILES: C1[C@H]([C@@H]2[C@@H](C(=O)N1)N=C(N2)N[C@H]3[C@@H]([C@@H]([C@H]([C@H](O3)CO)OC(=O)N)O)NC(=O)C[C@H](CCCNC(=O)C[C@H](CCCNC(=O)C[C@H](CCCNC(=O)C[C@H](CCCNC(=O)C[C@H](CCCN)N)N)N)N)N)O
InChI Key: SFBVRPSSMVXTDR-PTESPJIQSA-N
Can. SMILES: C1C(C2C(C(=O)N1)N=C(N2)NC3C(C(C(C(O3)CO)OC(=O)N)O)NC(=O)CC(CCCNC(=O)CC(CCCNC(=O)CC(CCCNC(=O)CC(CCCNC(=O)CC(CCCN)N)N)N)N)N)O
InChI:
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/198907
Citations:
  • https://www.jstage.jst.go.jp/article/yoken1948/3/1/3_1_25/_article
  • https://www.jstage.jst.go.jp/article/yoken1948/3/4/3_4_219/_pdf/-char/en
  • https://www.jstage.jst.go.jp/article/yoken1948/4/4/4_4_223/_article/-char/en

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