Compound ID | 3019

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Griseolutein B

Class: Natural product antibiotic

Agent Type: Natural product; Small molecule;
Spectrum of activity: Gram-positive
Mechanism of action: Unknown
Target Pathogen: Active against Staphylococcus aureus
Description: Natural product from Streptomyces griseoluteus; 100% survival of mice infected with Streptococcus pyogenes when treated with 2.5 mg of griseolutein; also shows antitrypanosomal activity; has a phenazine scaffold
Year first mentioned: 1953
Development status: Experimental
Chemical structure(s):
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Molecular weight:
Iso. SMILES:
InChI Key:
Can. SMILES: COC1=CC=C(C2=NC3=CC=CC(=C3N=C12)C(=O)O)COC(CO)O
InChI:
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/159640
Citations:
  • https://www.jstage.jst.go.jp/article/cpb1958/6/5/6_5_547/_article/-char/en
  • https://www.jstage.jst.go.jp/article/yoken1952/6/5/6_5_493/_article
  • https://www.jstage.jst.go.jp/article/antibioticsa/10/6/10_265/_article/-char/en

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