Compound ID | 3031
Taitomycin
Synonym(s): RP-9671
Class: Antimicrobial peptide
| Agent Type: | Natural product; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | Unknown |
| Target Pathogen: | Active against methicillin-resistant and -susceptible Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, Corynebacterium diphtheriae, Bacillus anthracis, and Neisseria gonorrhoeae (no activity against other Gram-negatives) |
| Description: | Natural product from Streptomyces afghaniensis (previously identified as Streptomyces sp. No. 772); haemolytic activity towards bovine blood cells at 250 mg/ml (vs MIC at <0.1 ug/ml) |
| Institute where first reported: | Research Laboratory, Taito Company, Ltd. |
| Year first mentioned: | 1959 |
| Development status: | Experimental |
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