Compound ID | 3043

Griseococcin

Class: Natural product antibiotic

Spectrum of activity: Gram-positive
Details of activity: Active against multidrug-resistant Staphylococcus aureus
Description: Natural product from Streptomyces sp.; shows weak synergistic effect with chloramphenicol; no cytotoxicity observed against HeLa cells at 100 ug/ml (highest tested); failed to show protective effect against staphylococcal infection in mice
Year first mentioned: 1962
Development status: Experimental

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