Compound ID | 3046

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Cirramycin

Class: Macrolide

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus, Streptococcus pneumoniae, Enterococcus faecalis, Bacillus anthracis, and Hemophilus influenzae
Description: Natural product from Streptomyces cirratus ; shows weak activity against Gram-negatives; erythromycin-resistant staphylococci are cross-resistant to cirramycin
Institute where first reported: Bristol-Banyu Research Institute, Ltd.
Year first mentioned: 1963
Development status: Experimental
Chemical structure(s):
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Molecular weight: 637.81
Iso. SMILES: CCC1C(C2C(O2)(/C=C/C(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC3C(C(CC(O3)C)N(C)C)O)C/C=N/NC(=O)C)C)C)C
InChI Key: BEYPIGLXIHAEAA-YSGQLIDXSA-N
Can. SMILES: CCC1C(C2C(O2)(C=CC(=O)C(CC(C(C(C(CC(=O)O1)O)C)OC3C(C(CC(O3)C)N(C)C)O)CC=NNC(=O)C)C)C)C
InChI:
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/9577442
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/28/6/28_6_401/_pdf
  • https://www.jstage.jst.go.jp/article/antibioticsa/16/2/16_59/_article/-char/en

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