Compound ID | 305
Epidermicin NI01
Class: Antimicrobial peptide
| Agent Type: | Natural product; Direct acting; Antibiofilm; |
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | Membrane-active agent. Membrane depolarising agent which prevents biofilm formation |
| Target Pathogen: | Active against Staphylococcus epidermidis, Staphylococcus saprophyticus, vancomycin-resistant and -susceptible Enterococcus faecalis, and methicillin-resistant and -susceptible Staphylococcus aureus |
| Description: | Natural product from Staphylococcus epidermidis; a bacteriocin |
| Institute where first reported: | Amprologix, Plymouth, UK; University of Manchester |
| Year first mentioned: | 2012 |
| Highest development stage: | Preclinical |
| Development status: | Experimental |
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