Compound ID | 3050
Danomycin
Class: Antimicrobial peptide
| Agent Type: | Natural product; |
| Spectrum of activity: | Gram-positive |
| Mechanism of action: | Unknown |
| Target Pathogen: | Active against Staphylococcus aureus, Corynebacterium xerosis, Bacillus anthracis, and Streptococcus pneumoniae |
| Propensity to select resistant mutants: | Yes, at 10^-5 mutation frequency at 35 ug/ml |
| Description: | Natural product from Streptomyces albaduncus; shows curative dose (CD50) comparable to penicillin G in treating Staphylococcus aureus infection in mice; a sideromycin |
| Institute where first reported: | Bristol-Banyu Research Institute, Ltd. |
| Year first mentioned: | 1964 |
| Highest development stage: | Preclinical |
| Development status: | Experimental |
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