Compound ID | 3058

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Aztreonam lysine (Cayston)

Class: Beta-lactam

Spectrum of activity: Gram-negative
Details of activity: Active against Pseudomonas aeruginosa; indicated for cystic fibrosis pulmonary infection and non�cystic fibrosis bronchiectasis
Description: Novel formulation of aztreonam suitable for aerosol delivery; a monobactam
Institute where first reported: Gilead Sciences
Year first mentioned: 2010
Highest developmental phase: Approved by FDA in 2010
Development status: Approved
Chemical structure(s):
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Molecular weight: 581.62
Iso. SMILES: C[C@H]1[C@@H](C(=O)N1S(=O)(=O)O)NC(=O)/C(=N\OC(C)(C)C(=O)O)/C2=CSC(=N2)N.C(CCN)C[C@@H](C(=O)O)N
InChI Key: KPPBAEVZLDHCOK-JHBYREIPSA-N
Can. SMILES: CC1C(C(=O)N1S(=O)(=O)O)NC(=O)C(=NOC(C)(C)C(=O)O)C2=CSC(=N2)N.C(CCN)CC(C(=O)O)N
InChI:
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/11204019
Citation: https://pubmed.ncbi.nlm.nih.gov/20658904/

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