Compound ID | 3068

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Cervimycin C

Class: Natural product antibiotic

Spectrum of activity: Gram-positive
Details of activity: Active against Staphylococcus aureus; targets DNA gyrase (bacterial topoisomerase inhibitor)
Description: Natural product from Streptomyces tendae; polyketide compound
Year first mentioned: 2024
Development status: Experimental
Chemical structure(s):
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Molecular weight: 1228.29
Iso. SMILES: C[C@@H]1[C@H](CC[C@@H](O1)O[C@H]2CC[C@@H](O[C@@H]2C)O[C@]34[C@H](CC5=CC6=C(C(=O)C=C(C6=O)OC)C(=C5C3=O)O)[C@H](C(=O)C(=C4O)C(=O)N)O[C@H]7CC[C@@H]([C@H](O7)C)O[C@H]8CC[C@@H]([C@@H](O8)C)O[C@H]9CC[C@@H]([C@@H](O9)C)O[C@H]1CC[C@@H]([C@@H](O1)C)OC(=O)C(C)(C)C(=O)O)O
InChI Key: CYKZTBKVWQAQLU-KSQSWLAPSA-N
Can. SMILES: CC1C(CCC(O1)OC2CCC(OC2C)OC34C(CC5=CC6=C(C(=O)C=C(C6=O)OC)C(=C5C3=O)O)C(C(=O)C(=C4O)C(=O)N)OC7CCC(C(O7)C)OC8CCC(C(O8)C)OC9CCC(C(O9)C)OC1CCC(C(O1)C)OC(=O)C(C)(C)C(=O)O)O
InChI:
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/54687465
Guide to Pharmacology: cervimycin C
Citation: https://journals.asm.org/doi/10.1128/msphere.00764-23

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