Compound ID | 3081

Leucylnegamycin

Class: Protein synthesis inhibitor

Spectrum of activity: Gram-negative
Details of activity: Active against Escherichia coli, Shigella sonnei, Salmonella typhosa, Klebsiella pneumoniae, and Pseudomonas fluorescens
Description: Natural product from Streptomyces purpeofuscus; suggested to be an intermediate product in biosynthesis of negamycin
Year first mentioned: 1971
Development status: Experimental
Chemical structure(s):
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Molecular weight: 361.44
Iso. SMILES: CC(C)C[C@@H](C(=O)NC[C@@H](C[C@H](CC(=O)NN(C)CC(=O)O)N)O)N
InChI Key: BRLOZZKKEWGIEL-UTUOFQBUSA-N
Can. SMILES: CC(C)C[C@@H](C(=O)NC[C@@H](C[C@H](CC(=O)NN(C)CC(=O)O)N)O)N
InChI: InChI=1S/C15H31N5O5/c1-9(2)4-12(17)15(25)18-7-11(21)5-10(16)6-13(22)19-20(3)8-14(23)24/h9-12,21H,4-8,16-17H2,1-3H3,(H,18,25)(H,19,22)(H,23,24)/t10-,11-,12+/m1/s1

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