Compound ID | 3101

Update compound information

ASK-753

Synonym(s): ASK753

Class: Protein synthesis inhibitor

Agent Type: Natural product; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Protein synthesis inhibitor. Aminoacyl-tRNA synthetase inhibitor (lysyl tRNA synthetase [LysRS] inhibitor)
Target Pathogen: Active against Staphylococcus aureus, Salmonella paratyphi, Escherichia coli, Klebsiella pneumonia, and Pseudomonas aeruginosa
Description: Natural product from Streptomyces sp. AS-K-53; iron-containing antimicrobial peptide
Year first mentioned: 1969
Development status: Experimental
External links:
Citations:
  • https://www.jstage.jst.go.jp/article/antibiotics1968/29/3/29_3_303/_article
  • https://www.jstage.jst.go.jp/article/antibiotics1968/27/11/27_11_874/_article/-char/en
  • https://www.jstage.jst.go.jp/article/antibiotics1968/22/3/22_3_106/_article

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