Compound ID | 3110

Antibiotic B-43

Class: Antimicrobial peptide

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus, Streptococcus pneumoniae, Streptococcus pyogenes, Escherichia coli, Klebsiella pneumoniae, and Salmonella typhimurium
Description: Natural product from Bacillus circulans; similar to polypeptin; lethal to mice when administered at 50 mg/kg via intraperitoneal route
Institute where first reported: Shionogi Research Laboratory, Shionogi & Co., Ltd.
Year first mentioned: 1976
Development status: Experimental

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