Compound ID | 3123

Update compound information

A26771B

Class: Macrolide

Spectrum of activity: Gram-positive
Details of activity: Active against Staphylococcus aureus and Streptococcus sp.; likely protein synthesis inhibitor
Description: Natural product from Penicillium turbatum; shows no antibacterial activity in mice infected with Staphylococcus aureus, Streptococcus pyogenes, and Streptococcus pneumoniae when administered subcutaneously
Institute where first reported: Lilly Research Laboratories, Eli Lilly and Company
Year first mentioned: 1977
Development status: Experimental
Chemical structure(s):
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Molecular weight: 382.45
Iso. SMILES: C[C@@H]1CCCCCCCCC[C@@H](C(=O)/C=C/C(=O)O1)OC(=O)CCC(=O)O
InChI Key: CAOCHWFVLJETKN-SADTYBKJSA-N
Can. SMILES: C[C@@H]1CCCCCCCCC[C@@H](C(=O)/C=C/C(=O)O1)OC(=O)CCC(=O)O
InChI: InChI=1S/C20H30O7/c1-15-9-7-5-3-2-4-6-8-10-17(16(21)11-13-19(24)26-15)27-20(25)14-12-18(22)23/h11,13,15,17H,2-10,12,14H2,1H3,(H,22,23)/b13-11+/t15-,17+/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/11143436
Citations:
  • https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9014984/
  • https://www.jstage.jst.go.jp/article/antibiotics1968/30/7/30_7_571/_article/-char/en

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