Compound ID | 3124

Glycinothricin

Class: Streptothricin

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus and Escherichia coli (including streptomycin-resistant strain)
Description: Natural product from Streptomyces griseus; derivative of antibiotic LL-AB 664
Institute where first reported: Fermentation Research Laboratories, Sankyo Co., Ltd.; Nagasaki University, Japan
Year first mentioned: 1977
Development status: Experimental
Chemical structure(s):
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Molecular weight: 459.45
Iso. SMILES: CN1C[C@H]([C@@H]2[C@@H](C1=O)N=C(N2)N[C@H]3[C@@H]([C@@H]([C@H]([C@H](O3)CO)OC(=O)N)O)N(C)C(=O)CN)O
InChI Key: IGGCBWFVVFZDLU-HZSGZFBJSA-N
Can. SMILES: CN1C[C@H]([C@@H]2[C@@H](C1=O)N=C(N2)N[C@H]3[C@@H]([C@@H]([C@H]([C@@H](CO)O3)OC(=O)N)O)N(C)C(=O)CN)O
InChI: InChI=1S/C17H29N7O8/c1-23-4-6(26)9-10(15(23)29)21-17(20-9)22-14-11(24(2)8(27)3-18)12(28)13(32-16(19)30)7(5-25)31-14/h6-7,9-14,25-26,28H,3-5,18H2,1-2H3,(H2,19,30)(H2,20,21,22)/t6-,7-,9-,10+,11-,12+,13+,14-/m1/s1

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