Compound ID | 3130
Sequanamycin 9
Synonym(s): SEQ-9
Class: Macrolide
| Details of activity: | Active against Mycobacterium tuberculosis |
| Description: | Semi-synthetic compound based on sequanamycin A (SEQ-503); shows activity against Mycobacterium tuberculosis in macrophages; shows efficacy against murine TB when combined with bedaquiline or bedaquiline and pretomanid |
| Institute where first reported: | Sanofi R&D; Evotec ID (LYON); Texas A&M University, College Station, TX, USA |
| Year first mentioned: | 2023 |
| Development status: | Experimental |
| External links: | |
| PubChem link: | https://pubchem.ncbi.nlm.nih.gov/substance/459280867 |
| Guide to Pharmacology: | SEQ-9 |
| Citation: | https://www.cell.com/cell/pdf/S0092-8674(23)00102-2.pdf |
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