Ionomycin

Synonym(s): SQ-23377  |  SQ23377

Class: Natural product antibiotic (polyether)

Spectrum of activity:	Gram-positive
Details of activity:	Active against Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, and Corynebacterium diphtheriae
Description:	Natural product from Streptomyces conglobatus
Institute where first reported:	Squibb Institute for Medical Research
Year first mentioned:	1978
Development status:	Experimental

Chemical structure(s):
Canonical SMILES:	C[C@H](C/C=C/[C@@H](C)[C@H]([C@@H](C)[C@H](C[C@@H]1CC[C@@](C)([C@H]2CC[C@@](C)([C@@H](C)O)O2)O1)O)O)C[C@@H](C)/C(=C/C(=O)[C@@H](C)C[C@@H](C)C[C@H](C)CCC(=O)O)/O
Isomeric SMILES:	C[C@H](CCC(=O)O)C[C@H](C)C[C@H](C)C(=O)/C=C(/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@H]([C@@H](C)[C@H](C[C@@H]1CC[C@@](O1)(C)[C@H]2CC[C@@](O2)(C)[C@@H](C)O)O)O)\O
InChI:	InChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42/h11,13,24-33,36-37,39,42-43,45,48H,12,14-23H2,1-10H3,(H,46,47)/b13-11+,34-24-/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+/m1/s1
InChI Key:	PGHMRUGBZOYCAA-ADZNBVRBSA-N
Structure link:	https://pubchem.ncbi.nlm.nih.gov/compound/6912226

External links:
Guide to Pharmacology:	ionomycin
Main Source:	https://www.jstage.jst.go.jp/article/antibiotics1968/31/9/31_9_815/_article/-char/en