Compound ID | 3134

Update compound information

Ionomycin

Synonym(s): SQ-23377  |  SQ23377

Class: Natural product antibiotic

Agent Type: Natural product; Small molecule;
Spectrum of activity: Gram-positive
Mechanism of action: Unknown
Target Pathogen: Active against Staphylococcus aureus, Streptococcus pyogenes, Streptococcus pneumoniae, and Corynebacterium diphtheriae
Description: Natural product from Streptomyces conglobatus; polyether scaffold
Institute where first reported: Squibb Institute for Medical Research
Year first mentioned: 1978
Development status: Experimental
Chemical structure(s):
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Molecular weight: 709.01
Iso. SMILES: C[C@H](CCC(=O)O)C[C@H](C)C[C@H](C)C(=O)/C=C(/[C@H](C)C[C@H](C)C/C=C/[C@@H](C)[C@H]([C@@H](C)[C@H](C[C@@H]1CC[C@@](O1)(C)[C@H]2CC[C@@](O2)(C)[C@@H](C)O)O)O)\O
InChI Key: PGHMRUGBZOYCAA-ADZNBVRBSA-N
Can. SMILES: C[C@H](C/C=C/[C@@H](C)[C@H]([C@@H](C)[C@H](C[C@@H]1CC[C@@](C)([C@H]2CC[C@@](C)([C@@H](C)O)O2)O1)O)O)C[C@@H](C)/C(=C/C(=O)[C@@H](C)C[C@@H](C)C[C@H](C)CCC(=O)O)/O
InChI: InChI=1S/C41H72O9/c1-25(21-29(5)34(43)24-35(44)30(6)22-27(3)20-26(2)14-15-38(46)47)12-11-13-28(4)39(48)31(7)36(45)23-33-16-18-41(10,49-33)37-17-19-40(9,50-37)32(8)42/h11,13,24-33,36-37,39,42-43,45,48H,12,14-23H2,1-10H3,(H,46,47)/b13-11+,34-24-/t25-,26-,27+,28-,29-,30+,31+,32-,33+,36+,37-,39-,40+,41+/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/6912226
Guide to Pharmacology: ionomycin
Citation: https://www.jstage.jst.go.jp/article/antibiotics1968/31/9/31_9_815/_article/-char/en

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