Compound ID | 3158

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Antlermicin A

Class: Natural product antibiotic

Spectrum of activity: Gram-positive
Details of activity: Active against Gram-positive bacilli; disrupts integrity of cell membrane; membrane-active agent
Description: Natural product from Micromonospora chalcea subsp. kazunoensis; an ionophore
Year first mentioned: 1980
Development status: Experimental
Chemical structure(s):
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Molecular weight: 1313.48
Iso. SMILES: CC1CC(C(C2C1C/3(C(C=C2)/C(=C\CC(/C(=C\C4C(C=C(CC45C(=O)/C(=C3/O)/C(=O)O5)C=O)O)/C)OC6CC(C(C(O6)C)NC(=O)OC)(C)[N+](=O)[O-])/C)C)OC7CC(C(C(O7)C)OC(=O)C)OC8CCC(C(O8)C)OC9CC(C(C(O9)C)OC1CCC(C(O1)C)O)O)C
InChI Key: QOPRNPHPHOIJNY-NUIAMOMSSA-N
Can. SMILES: C/C/1=C/CC(/C(=C\C2C(C=C(CC23C(=O)/C(=C(\C4(C)C1C=CC5C4C(C)CC(C)C5OC6CC(C(C(C)O6)OC(=O)C)OC7CCC(C(C)O7)OC8CC(C(C(C)O8)OC9CCC(C(C)O9)O)O)/O)/C(=O)O3)C=O)O)/C)OC%10CC(C)(C(C(C)O%10)NC(=O)OC)[N+](=O)[O-]
InChI: InChI=1S/C67H96N2O24/c1-30-14-18-47(88-54-28-65(11,69(79)80)60(38(9)86-54)68-64(78)81-13)31(2)23-43-45(73)24-40(29-70)27-67(43)62(76)55(63(77)93-67)61(75)66(12)42(30)16-15-41-56(66)32(3)22-33(4)57(41)92-53-26-49(59(37(8)85-53)87-39(10)71)90-50-21-19-48(35(6)83-50)89-52-25-46(74)58(36(7)84-52)91-51-20-17-44(72)34(5)82-51/h14-16,23-24,29,32-38,41-54,56-60,72-75H,17-22,25-28H2,1-13H3,(H,68,78)/b30-14-,31-23-,61-55-
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/54724658
Citation: https://www.jstage.jst.go.jp/article/antibiotics1968/33/2/33_2_244/_article/-char/en

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