Compound ID | 3172
Imidazo [4,5b] [1,8] naphthyridine derivative
Class: Small molecule antibacterial agent
| Agent Type: | Synthetic; Small molecule; Direct acting; |
| Spectrum of activity: | Gram-positive & Gram-negative |
| Mechanism of action: | DNA synthesis inhibitor. Binds to bacterial topoisomerase II; bacterial topoisomerase inhibitor |
| Target Pathogen: | Active against Staphylococcus aureus, Escherichia coli, Shigella flexneri, and Proteus mirabilis |
| Institute where first reported: | Research Institute, Daiichi Seiyaku Co., Ltd. |
| Year first mentioned: | 1980 |
| Development status: | Experimental |
| External links: | |
| Citation: | https://www.jstage.jst.go.jp/article/cpb1958/28/1/28_1_235/_article/-char/en |
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