Compound ID | 3180

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Oganomycin A

Class: Beta-lactam (cephamycin)

Spectrum of activity: Gram-negative
Details of activity: Active against Escherichia coli, Klebsiella pneumoniae, Salmonella sp., and Proteus sp.
Description: Natural product from Streptomyces oganonensis; cephamycin-type
Institute where first reported: Central Research Laboratories, Yamanouchi Pharmaceutical Co., Ltd.
Year first mentioned: 1981
Development status: Experimental
Chemical structure(s):
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Molecular weight: 629.62
Iso. SMILES: CO[C@@]1([C@@H]2N(C1=O)C(=C(CS2)COC(=O)/C=C/C3=CC=C(C=C3)OS(=O)(=O)O)C(=O)O)NC(=O)CCC[C@H](C(=O)O)N
InChI Key: WZUOYYCVBUQXEE-CULMAWHJSA-N
Can. SMILES: CO[C@]1(C(=O)N2C(=C(COC(=O)/C=C/C3=CC=C(C=C3)OS(=O)(=O)O)CS[C@H]12)C(=O)O)NC(=O)CCC[C@H](C(=O)O)N
InChI: InChI=1S/C24H27N3O13S2/c1-38-24(26-17(28)4-2-3-16(25)20(30)31)22(34)27-19(21(32)33)14(12-41-23(24)27)11-39-18(29)10-7-13-5-8-15(9-6-13)40-42(35,36)37/h5-10,16,23H,2-4,11-12,25H2,1H3,(H,26,28)(H,30,31)(H,32,33)(H,35,36,37)/b10-7+/t16-,23-,24+/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/15572074
Citation: https://www.jstage.jst.go.jp/article/antibiotics1968/34/11/34_11_1507/_article/-char/en

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