Compound ID | 3183

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C-19393 E5

Class: Beta-lactam (carbapenem)

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterobacter cloacae, and Salmonella typhimurium
Description: Natural product from Streptomyces griseus subsp. cryophilus; carbapenem-type
Institute where first reported: Takeda Chemical Industries, Ltd.
Year first mentioned: 1982
Development status: Experimental
Chemical structure(s):
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Molecular weight: 328.34
Iso. SMILES: C[C@H](C1[C@H]2CC(=C(N2C1=O)C(=O)O)S(=O)/C=C/NC(=O)C)O
InChI Key: OLJZNOCSKZHZQJ-QGKPYDHGSA-N
Can. SMILES: C[C@H](C1[C@H]2CC(=C(C(=O)O)N2C1=O)S(=O)/C=C/NC(=O)C)O
InChI: InChI=1S/C13H16N2O6S/c1-6(16)10-8-5-9(22(21)4-3-14-7(2)17)11(13(19)20)15(8)12(10)18/h3-4,6,8,10,16H,5H2,1-2H3,(H,14,17)(H,19,20)/b4-3+/t6-,8-,10?,22?/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/145720558
Citation: https://www.jstage.jst.go.jp/article/antibiotics1968/35/8/35_8_957/_article/-char/en
Patent: EP0055929A1

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