Compound ID | 3184

Update compound information

AT-265

Synonym(s): AT265  |  AT 265

Class: Protein synthesis inhibitor

Agent Type: Natural product; Small molecule; Direct acting;
Spectrum of activity: Gram-positive & Gram-negative
Mechanism of action: Protein synthesis inhibitor
Target Pathogen: Active against Staphylococcus aureus and Escherichia coli
Description: Natural product from Streptomyces rishiriensis; chlorine containing sulfamoyl nucleoside antibiotic
Year first mentioned: 1982
Development status: Experimental
Chemical structure(s):
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Molecular weight: 380.77
Iso. SMILES: C1=NC2=C(N=C(N=C2N1[C@H]3[C@@H]([C@@H]([C@H](O3)COS(=O)(=O)N)O)O)Cl)N
InChI Key: JHUGCRSKMUFKHR-UUOKFMHZSA-N
Can. SMILES: C([C@@H]1[C@H]([C@H]([C@H](N2C=NC3=C2N=C(Cl)N=C3N)O1)O)O)OS(=O)(=O)N
InChI: InChI=1S/C10H13ClN6O6S/c11-10-15-7(12)4-8(16-10)17(2-14-4)9-6(19)5(18)3(23-9)1-22-24(13,20)21/h2-3,5-6,9,18-19H,1H2,(H2,12,15,16)(H2,13,20,21)/t3-,5-,6-,9-/m1/s1
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/125623
Citation: https://www.jstage.jst.go.jp/article/antibiotics1968/35/8/35_8_939/_article/-char/en

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