Compound ID | 3186

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PS-8

Class: Beta-lactam (carbapenem)

Spectrum of activity: Gram-positive  &  Gram-negative
Details of activity: Active against Staphylococcus aureus, Streptococcus pneumoniae, and beta-lactamase producing Enterobacter cloacae
Description: Natural product from Streptomyces cremeus subsp. auratilis; carbapenem-type
Institute where first reported: Sanraku-Ocean Co., Ltd. Central Research Laboratories
Year first mentioned: 1982
Development status: Experimental
Chemical structure(s):
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Molecular weight: 310.37
Iso. SMILES: CC(C)C1C2CC(=C(N2C1=O)C(=O)O)S/C=C/NC(=O)C
InChI Key: LMCMRDZMDLAQJY-SNAWJCMRSA-N
Can. SMILES: CC(C)C1C2CC(=C(C(=O)O)N2C1=O)S/C=C/NC(=O)C
InChI: InChI=1S/C14H18N2O4S/c1-7(2)11-9-6-10(21-5-4-15-8(3)17)12(14(19)20)16(9)13(11)18/h4-5,7,9,11H,6H2,1-3H3,(H,15,17)(H,19,20)/b5-4+
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/6439630
Citation: https://www.jstage.jst.go.jp/article/antibiotics1968/35/6/35_6_763/_article/-char/en

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