Compound ID | 3199

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Morinamide

Synonym(s): Morphazinamide  |  Piazofolina  |  Nicoprazin  |  Morphazin

Class: Mycolic acid synthesis inhibitor

Details of activity: Active against Mycobacterium tuberculosis; mycobacterial fatty acid synthesis (targets fatty acid synthase FAS I)
Description: Synthetic compound; N-morpholino-4'methylamide pyrazin-carbonic acid; inferior to pyrazinamide as monotherapy in treating mice with chronic tuberculosis
Year first mentioned: 1962
Development status: Unknown
Chemical structure(s):
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Molecular weight: 222.24
Iso. SMILES: C1COCCN1CNC(=O)C2=NC=CN=C2
InChI Key: GVTLAVKAVSKBKK-UHFFFAOYSA-N
Can. SMILES: C1=NC=C(C(=O)NCN2CCOCC2)N=C1
InChI: InChI=1S/C10H14N4O2/c15-10(9-7-11-1-2-12-9)13-8-14-3-5-16-6-4-14/h1-2,7H,3-6,8H2,(H,13,15)
External links:
PubChem link: https://pubchem.ncbi.nlm.nih.gov/compound/70374
Citations:
  • https://doi.org/10.1159/000220356
  • https://karger.com/cth/article/9/3/158/89370/Comparison-of-the-Antituberculous-Activity-of

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