Compound ID | 3204
VA-2
Synonym(s): VA2 | VA 2
Class: DNA synthesis inhibitor
| Spectrum of activity: | Gram-positive & Gram-negative |
| Details of activity: | Broad-spectrum activity including Mycobacterium tuberculosis |
| Description: | Natural product from Micromonospora verruculosa MCRL 0404; part of the M-92 antibiotic complex; protects mice from Staphylococcus aureus infection when administered intraperitoneally; shows cytotoxicity towards HeLa S-3 cells at 0.001 mg/L (MIC at 0.00035 mg/L) |
| Institute where first reported: | Microbiological Research Laboratory, Tanabe Seiyaku Co., Ltd. |
| Year first mentioned: | 1982 |
| Development status: | Experimental |
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